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Oct 9, 2023Liked by David Hugh-Jones

Neanderthal-Derived Genetic Variation in Living Humans Relates to Schizophrenia Diagnosis, to Psychotic Symptom Severity, and to Dopamine Synthesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454493/

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Hi David, I sent you a message on Twitter!

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When a disease responds to antihistamines, stands to reason it is immunological or at least mast cell mediated. So at MHC and other subcompatibilities (eg mitonuclear) arising in urban (recent mixing under relaxed mortality) and more distantly admixed populations. Being white is suggestive of a less admixed state. Just thinking out loud. Idk really that there’s reason to be depressed but hope for a lot of biomedical progress. Hope it’s less mad than Russian physio. But prob not. Cheers again. Your idiosyncratic prosody just attracts the crazies I guess.

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author

> Your idiosyncratic prosody just attracts the crazies I guess.

I might have to use this quote as a front-page recommendation.

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Schizophrenia seems to me to be a mostly postural issue; see here:

https://eharding.substack.com/p/why-does-russian-physical-therapy

There are, as far as I can tell, two types of schizophrenia, bicameral (named so after the Jaynes book) and hyperextended/flatback (which you don't want). Schizophrenia, I suspect, is most likely to appear among ethnicities poorly adapted to flatback posture (which, for obvious reasons, is more common in the cities than in the country).

Black people seem to be unusually adapted to nose sleeping (rather than the chin sleeping common among the ancestors of today's Northeast Euros -the "mystery of the chin" is deliberately kept secret due to censorship from the intelligence agencies).

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author

This seems deeply confused, and the link even more so.

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Try it out; see what happens.

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Any links to “chin sleeping”?

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There are very, very few that I've been able to find. Here is one example from the late 19th century:

https://cdn.discordapp.com/attachments/755126754581938217/1114690323554242580/Screenshot_17.png

I think I remember from somewhere that the recommended sleeping position for soldiers has been sleeping on the stomach/chin with one arm extended, but I haven't been able to find documentation of this.

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Every single part of this is wrong.

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It's been a day; I would like you to please explain how I'm wrong.

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Schizophrenia is not a postural problem, for starters.

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That's an assertion without evidence. I suggest trying the Russian physical therapy yourself.

How do you know it's not a postural problem?

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In this case, the burden of proof is on the person (you) claiming a novel conceptualization of the illness as well as treatment. Everything we currently know points toward it being a brain illness.

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"In this case, the burden of proof is on the person (you) claiming a novel conceptualization of the illness as well as treatment."

Personal experience. And, as I said, I suggest trying it yourself (or experiment with volunteers) -there is no substitute for self-experimentation. You should start to see effects at around three days to a week, with full-blown bicameralism (again, read the Jaynes book) being seen ~2 months. Fair warning -do not do anything stupid.

The question for you is why there is so much censorship re: the purpose of the chin in the U.S.

"Everything we currently know points toward it being a brain illness."

After my experience with hyperextended/flatback schizophrenia in 2020 (due to shoulder collapse likely due to prolonged mouse use) I had the "normal MRI".

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Explain, poster.

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The medical genetics research is essential, and so interesting. One example that every medical student knows: People who have the HLA (human leukocyte antigen) allele B*1502 and are given the anticonvulsant carbamazepine are far more likely than others to develop a potentially fatal skin reaction called Steven Johnson Syndrome/toxic epidermal necrolysis. This was first demonstrated among Han Chinese who had this allele. But other east and south Asians may also have high or intermediate risk as well, and it isn't clear the B*1502 allele has the same effects for various ethnic groups, e.g. a European with the B*1502 allele doesn't seem to have the elevated risk that a Han Chinese would.

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